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Discussion forum - 49th ERA-EDTA Congress
    Topic - Hypertension

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Poster: 37
Visits: 723
Title: Promoter Polymorphism of the IL-6 (C-174G) gene and the estimation of Metabolic Syndrome Occurrence among a cohort of patients with Hypertension
Authors: ANDREI ALKMIM TEIXEIRA , MARIE BEATA QUINTINO, CASSIO JOSE RODRIGUES, ARTUR BELTRAME RIBEIRO, MARCELO COSTA BATISTA
Centre: UNIFESP / EPM

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PROMOTER POLYMORPHISM OF THE IL-6 (C-174G) GENE AND THE ESTIMATION OF METABOLIC SYNDROME OCCURRENCE AMONG A COHORT OF PATIENTS WITH HYPERTENSION

ANDREI ALKMIM TEIXEIRA
Thread initiator
Subspeciality
Reg: 5/9/2012 6:07:00 PM

 Comment# 1

Metabolic Syndrome (SM) is associated with subsequent diabetes and cardiovascular events.An overproduction of cytokines could be involved in the onset of early inflammation state in MS and cardiovascular disease.The 174G/C SNP of IL-6 has been related with elevated levels of pro-inflammatory cytokines in humans and could represent a marker to identify individuals at increased risk of cardiovascular diseases. We examined if the -174 G/C IL-6 genetic polymorphism is associated with MS ocurrence in a cohort of hypertensive patients.
Comment added on 5/9/2012 6:07:00 PM 
     
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